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The latest findings further revealed that the HECT domain-containing ubiquitin E3 ligase HUWE1 was also an underlying protective modulator that could combat ferroptosis and abnormal iron accumulation by diminishing the amassing of TfR1, reducing the risk of ALF (Wu et al., 2022)

J Inherit Metab Dis 34:1732 Stipanuk MH, Coloso RM, Garcia RAG, Banks MF (1992) Cysteine concentration regulates cysteine metabolism to glutathione, sulfate and taurine in rat hepatocytes

10.1007/BF01700146

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