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Description
Despite numerous pre-clinical studies reporting positive pharmacodynamics of turmeric extracts and curcumin, the main issues in translating the pharmacological effects to clinical efficacy have been to overcome its poor pharmacokinetics and to deliver significant amounts of the biologically relevant forms of the actives to various tissues

This stress respond is initiated by impaired protein folding process, which is triggered by covalent binding of NAPQI to the ER proteins [119]

2016;167:829842.e813

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