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Restricted Delivery of Talazoparib Across the BloodBrain Barrier Limits the Sensitizing Effects of PARP Inhibition on Temozolomide Therapy in Glioblastoma
Oxidative stress in prostate hyperplasia and carcinogenesis
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Furthermore, HIF1 upregulates MIX Interactor 1, a transcription factor that represses cMYC, leading to a decrease in mitochondria biogenesis and mass, further decreasing pyruvate oxidation [151, 154]
