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Ferroptosis, an iron-dependent form of regulated cell death driven by lethal lipid peroxidation, offers a distinct mechanism to overcome drug resistance in OS cells, which frequently exhibit metabolic dependency on iron

Besides diabetes and high blood pressure, the following additional health conditions may also contribute to CKD 1 : Cardiovascular disease Systemic or kidney infections Immune system conditions (eg, lupus) Inflammation of the glomeruli (tiny filters) in the kidneys Inherited kidney disease (eg, polycystic kidney disease) Congenital defects (eg, kidney malformation, urinary tract obstruction) Medications and toxins (eg, prolonged medication, chemical, or street drug exposure) Factors such as those described above and various others can contribute to the decline in kidney function characteristic of CKD

ZhangZWangXWangZZhangZCaoYWeiZet alDihydroartemisinin alleviates hepatic fibrosis through inducing ferroptosis in hepatic stellate cells

One of their important functions is the metabolism of two neurotoxic agents: ammonia and glutamate, using the enzyme called glutamine synthetase (GS)