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In contrast, zinc deficiency appears to enhance the differentiation and maturation of HL-60 cells into macrophages when stimulated by 1 , 25-dihydroxyvitamin D D(3) (1,25D(3)) [218]

Table 1 Effects of bioactive natural product extract pretreatment in ALI

Due to the fact that changes in calcitriol levels alter plasma calcium and PTH levels it is not clear what the exact mode of action is for calcitriol relative to renal phosphate retention

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