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Zhang B, et al
ROS are continuously produced in vivo by all body tissues

J Environ Public 2012:835059 Hotchkiss RS, Moldawer LL, Opal SM, Reinhart K, Turnbull IR, Vincent JL (2016) Sepsis and septic shock

CAT represents an important enzymatic system able to inactivate ROS and their by-products [16]

Additionally, the presence of a mechanism in a petri dish or mouse model does not guarantee clinical relevance in humans
