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(iii) Required production levels : structural studies require higher protein production levels that can be rapidly achieved with a larger fusion tag, which has strong translational initiation signals, whereas the study of physiological interactions demands for lower production levels and small tags (Malhotra, 2009)

Fahmy, E.M., N.M

Also, it has been shown that MDMA metabolites might create an inhibitor complex with the cytochrome P 450 2D6 enzyme, leading to toxicity in repetitive doses

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