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During the photoactivation process, the inactive receptor undergoes a series of concerted conformational changes that lead to the active state, named Metarhodopsin II (Meta II)

These short peptides demonstrate direct DNA interaction and nuclear penetration in cell culture models[16]

Moreover, the skin transcriptome found that lysosomes activated after oral administration of CPs may be an important pathway for CPs in anti-skin aging, and is worthy of further research

To achieve satisfactory results, they should be used in conjunction with standard pharmacology or phototherapy

Arterioscler Thromb Vasc Biol 17 : 20742081