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DARs (DNA reachable regions) are genomic regions that exhibit a more open chromatin structure, where histone modifications play a pivotal role in facilitating the binding of transcription factors and other regulatory proteins to DNA, thereby regulating gene expression
It is unknown if asymptomatic patients treated with L-Carnitine could still be susceptible to cardiac arrhythmia because of undiagnosed myocardial damage and fibrosis due to carnitine deficiency
The Kennedy pathway may also be accelerated to compensate for the inhibition of fatty acid synthesis 60
Yamanaka S
