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[26] [27] On a dose-by-dose basis, tramadol has about one-tenth the potency of morphine (thus 100 mg is commensurate with 10 mg morphine but may vary) and is practically equally potent when compared with pethidine and codeine

Combined with Vitamin C boosting collagen synthesis and antioxidants promoting skin renewal, it helps improve appearance of acne scars over time

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However, while this initial hepatic fat accumulation represents a key early event, it is insufficient on its own to drive disease progression