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Given that hepsin / mice were reported to have elevated mRNA levels of mitochondrial Cpt1b , Cpt2 , and Cox7a1 in adipose tissues compared with wild-type mice, suggesting a regulatory role for hepsin in metabolism (Li et al

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In the brain and body, glutamine contributes to: Nitrogen transport between tissues Regulation of acid-base balance Gluconeogenesis (production of glucose from non-carbohydrate sources) Serving as a precursor to nucleotide bases and the antioxidant glutathione (Castell et al., Nutrition ) These functions highlight the importance of maintaining adequate glutamine levels, especially when under metabolic stress or physical exertion

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European Molecular Biology Organization, 2002;3(6):527531