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As with nails, hair needs keratin, which becomes limited with CKD

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Ambroxol, a cough suppressant widely used in clinical practice, has recently been identified as a molecular chaperone that stabilizes and enhances -glucocerebrosidase activity, offering a unique potential strategy for disease-modifying therapy in PD

On the other hand, free phenolics are digestible in the small intestine while bound phenolic compounds are not absorbed (in the small intestine) and reached in the large intestine where they pass the fermentation process (by colon microbiota) and liberate bound phenolic compounds