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N Engl J Med 313 : 709715

Vitamin B12 is essential to growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis
Onset may take slightly longertypically a few daysas it primarily targets mitochondrial energy production

Most people having B12 injections (intramuscular) will see an improvement in the first 24 hours, but the hematological response, including the quick production of new red blood cells, may take several days to months for a full response
