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When activated by microbial indoles, it stimulates ILCs and T helper 17 (Th17) cells to produce interleukin-22 (IL-22), a key cytokine that reinforces epithelial barrier function by promoting epithelial cell proliferation and inducing the expression of antimicrobial peptides (72, 73)

For example, peroxidases can be used for the treatment of industrial waste waters

However, the retinal vasculature and cerebral vasculature share the same embryonic origin, and many similarities have been found in the pathologies affecting the two tissues

211,212 Moreover, after revealing the crystal structure of SIRT5, researchers found that SIRT5 is also a lysine desuccinylase and demalonylase

In AMD, the macula slowly becomes damaged due to an accumulation of waste material in the retinal tissue
