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In line with this, studies indicate that folate intake and availability in mammals impact the methylation and demethylation patterns of the genome during genetic imprinting

Similarly, enhancing endogenous mechanisms of neuronal resilience, such as antioxidant defenses, trophic support, and mitochondrial biogenesis, may provide additional protection against ongoing insult [1012]

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10.1186/s12934-022-01945-8 [DOI] [PMC free article] [PubMed] [Google Scholar] Demirtas, M

Those with a severe deficiency may require a 5000 mcg dose