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Cooper, C.E

N.J.Murray, M.P.Williamson, Conformational study of a salivary proline-rich protein repeat sequence, Eur.J.Biochem., 1993

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In the papers discussion, the authors wrote: Chronoferroptosis could explain the prolonged prodromal period between initial iron accumulation and GSH depletion and eventual neuronal loss in neurodegenerative diseases, thereby defining a critical therapeutic window for early intervention before cells transition to irreversible degeneration. There may be a long stretch of time before neurons die when they are still reachable

In the physiological state, thyroid hormones regulate the expression of genes needed for nerve cell differentiation, migration, and myelin formation