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"Presence of mycotoxins in milk thistle food supplements: a review." Toxins (Basel)

The degraded products may trigger or produce oxidative metabolic reactions, which aggravate the damage of substantia nigra

1.2 10 5 SHSY-5Y cells were subjected to similar treatment as above except 1 mM MPP + (for 24 h) was used to induce ROS

Finally, the model also integrates blood flow and dynamic exchanges between the vasculature and the neurons and glia, thereby allowing research questions related to nutrient supply to the brain to be addressed

This in turn enhances the activity of pro-inflammatory cytokines like TNF- and leukocytes