glutathione stransferase antioxidant Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Overexpression of Glutathione S-Transferases in
Description
As suggested by GPx-1's effect on cell growth and apoptosis reviewed in section IV, GPx-1 overexpression may have an antitumorogenic effect in some cancers theoretically by limiting oxidants (234), whereas it may allow for the survival of transformed cells in other cancers by limiting apoptotic mechanisms (238)

Another study also reported that EDV alleviated depressive-like behaviors by reversing the levels of GSH (Montazeri et al., 2023)

Regulatory T cells in SLE: biology and use in treatment

Balanced hormones are essential for ovulation in individuals with ovaries and sperm production in individuals with testes

These insights can help inform provider conversations about personalized antioxidant strategies, though genetic screening does not predict exact treatment response
