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Enhanced acetylation of H3 and H4, which are core histones of nucleosomes, plays an essential role in remodeling chromatin and converting genes to an active state 23
doi: 10.1021/jacs.8b01462 18 ChenW.WuZ.ChengZ.ZhangY.LuoQ.YinM
Eur J Drug Metab Pharmacokinet
Thus, there is a limit to how much can be taken up through this mechanism3
