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In addition, interestingly, the exhibited circulating levels of -endorphin in patients with chronic lower back pain are low [71,72]
If not, the absorption rate is likely very low
Determining the correct dosage depends on individual health goals and conditions
10.1016/j.abb.2006.02.016 [DOI] [PubMed] [Google Scholar] 14.Shimizu N, Hamada Y, Morozumi R, Yamamoto J, Iwai S, Sugiyama KI, Ide H, Tsuda M (2023) Repair of topoisomerase 1-induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium binding
doi: 10.1016/j.gde.2008.02.003 44 NewsholmeP