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Patrick, A

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[2] Mechanistic studies suggest that AOD-9604 may upregulate the expression of 3-adrenergic receptors (3-AR) in adipocytes, with elevated 3-AR expression potentially contributing to augmented lipolytic sensitivity in adipose tissue

Morning dosing allows the peptide to preemptively bind NNMT before this activity surge, extending the duration of enzyme inhibition across the metabolic active hours of the day

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