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10.1074/jbc.M207680200 J
Increased G6PD activity, which is the gatekeeping enzyme of the pentose phosphate pathway [69], and xanthine suggest an increased turnover rate for purine nucleosides, which may arise from the increased DNA damage from continuous exposure to tamoxifen
YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6
[PubMed: 18363546] 270
NLRP3 senses a wide array of endogenous and exogenous danger signals, including microbial products, environmental toxins, and host-derived DAMPs, making it a central player in inflammatory responses
