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10.1093/nar/gki856 18 BartekovaM.BarancikM.FerenczyovaK.DhallaN

doi: 10.1186/s12890-021-01675-4 [DOI] [PMC free article] [PubMed] [Google Scholar] 145.Olveira C, Olveira G, Gaspar I, et al

This hypothesis suggests that persulfides act as scavengers of one/two-electron oxidants and electrophiles due to their higher reactivity in comparison to corresponding thiols [215,216,217]

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Consistent with this model, we observed an increase in phosphorylated (inactive) PDH in hPSCs cultured at 5% O 2 compared to 21% O 2 , indicating reduced TCA cycle activity and mitochondrial respiration under low oxygen conditions
