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Declining estrogen reduces its natural protective effect on cartilage and connective tissue
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Microtubules formed by the polymerization of - and -tubulin dimers are ubiquitous cytoskeletal fibers in cells and are instrumental in maintaining ventricular shape (104)
Many of these neuroadaptive changes associated with dependence are integral to brain reward and stress systems (e.g., Hansson et al., 2008
