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Based on a comprehensive analysis of the literature, we propose that BACH1 is a typical context-dependent transcription factor, and its function is strongly regulated by the intracellular redox state: ROS levels and heme metabolism significantly influence the expression and activity of BACH1
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In addition, CD38 promotes the stimulation of CLL cells by activating the AKT/SYK/Mcl-1 signaling pathway
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