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While most people can benefit from this pairing, certain groups will see the most significant impact

Therefore, we transduced GCs with ChR2-tdTomato and chronically activated ChR2-expressing GCs using a low frequency protocol (5 pulses with 10 ms pulse length at 12.5 Hz every hour) with an AP frequency in their physiological activity range 50
The presence of chronic hyperglycemia, insulin resistance, oxidative stress, and pro-inflammatory mechanisms contribute to endothelial dysfunction in patients with diabetes mellitus (61)

That depends on your situation

, Begum G., and Rose C
