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The spliced bZIP60 mRNA is translated, the protein translocates to the nucleus and activates directly UPR genes such as genes encoding chaperones of the HSP70 family called BIPs (luminal-binding proteins)

Proteomic analysis of mouse astrocytes and their secretome by a combination of FASP and StageTipbased, high pH, reversedphase fractionation

Fas (CD95)/FasL (CD178) system during ageing
Adv Exp Med Biol 527:10512 OFarrell K et al (2017) Inhibition of the kynurenine pathway protects against reactive microglial-associated reductions in the complexity of primary cortical neurons

10.1177/2211068214561025 J