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Roles of IGF-1, IGF-1R, and IGFBPs in vascular smooth and endothelial cells IGF-1 and IGF-1R are expressed by vascular smooth muscle cells (VSMCs), endothelial cells (ECs), and macrophages (34), and together with different IGFBPs, they are considered significant regulators of atherosclerosis pathophysiology whose expression is downregulated in atherosclerotic lesions (4850)

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Moreover, combination therapy has the potential to enhance the number of anticancer targets and exert a synergistic effect

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5-Amino-1MQ for Muscle Repair Since 5-amino-1MQ inhibits NNMT in skeletal muscle and enhances the activity of GLUT4, the molecule may represent a promising intervention to improve workout capacity and physical performance

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(2001) Cannabinoids reduce levodopa-induced dyskinesia in Parkinsons disease: a pilot study

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Accumulating evidence suggested that the imbalance of Bacteroidetes and Firmicutes ratio contributed to the development of chronic pain (Garvey, 2023)

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