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This positive feedback regulatory loop mechanism causes antioxidant protection in the brain [75]

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The different CRP isoforms may explain their protective and destructive effects, with nCRP being predominantly anti-inflammatory inducing Th2/M2 responses, while mCRP being mainly proinflammatory inducing Th1/M1 responses (146, 161165)

[DOI] [PMC free article] [PubMed] [Google Scholar] 146.Weissman A.M

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