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Description
Gianotti-Crosti syndrome is characterized by a symmetric, monomorphic rash consisting of flat-topped, pink-red papules which erupt over the thighs and buttocks and gradually spread to extensor surfaces of the arms and, eventually, the face [Figure 11]

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34 The observation that TcdA could potentiate the activity of TcdB suggested that the toxins might act synergistically, with TcdB-mediated effects on the host occurring only once TcdA had caused prior damage to the intestinal epithelium

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