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Vitamin D plays a pivotal role in calcium metabolism and bone mineralization

Indeed, upon genotoxic stress, phosphorylated-CCAR2 increases its binding to SIRT1 and inhibits SIRT1 activity (56)

The MTHFR (methylenetetrahydrofolate reductase) gene provides instructions for making an enzyme that converts folate into its active form, L-methylfolate

doi: 10.1128/mBio.03134-21 32 MishraBBMoura-AlvesPSonawaneAHacohenNGriffithsGMoitaLFet al

Glutathione offers comprehensive antioxidant protection, binding to a wide array of damaging molecules, including reactive oxygen species (ROS), lipid peroxides, xenobiotics, pesticides, mycotoxins, oxidized vitamin E, oxidized vitamin C, methylmercury, medications, heavy metals, and other harmful substances