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pylori infection or medications), cobalamin absorption from food may be impaired (because the lack of the normal acidic environment of the stomach impedes the release of cobalamin from dietary proteins), but unbound cobalamin (eg, in supplemental vitamin preparations) will still be absorbed normally

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Another study was conducted similarly in both obese and lean mice

It can take many years (approx 20) to develop a deficiency disease in those altering their diet to one lacking in B12 due to reabsorbtion however, if failure to absorb leads to B12 deficiency disease occur within a few years (3-4)

It falls under the S0 category of Non-Approved Substances, which is a catch-all classification for any pharmacological substance that isnt approved for human therapeutic use and is not addressed elsewhere on the list