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doi: 10.1016/j.plipres.2021.101140 116 ChenYQPottanatTGSiegelRWEhsaniMQianYWZhenEYet al

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Growth factors outside of the platelet-derived growth factor (PDGF) family employ reactive oxygen species/Src family kinases to activate PDGF receptor alpha and thereby promote proliferation and survival of cells

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This is fundamentally different from regular weight loss, where fat cells merely shrink but remain in place

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However, in recent years its role in glucose control and in T2D risk or treatment has received increasing attention

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Intestinal injuries can be caused by numerous factors: Hemorrhoids: enlarged blood vessels in or around the anus Colon polyps: a small clump of cells that form in the colon Anal fissures: a tear in the lining of the anus Diverticular bleeding: diverticula (small pouches) in the colon rupture, leading to diverticulitis Tumors: abnormal growth of tissue, may be benign or malignant Ulcers: intestinal sores common in IBD, may also be present in the esophagus, stomach, duodenum, colon or rectum Excessive straining: too much force to relieve solid waste Arteriovenous malformations: arteries or veins rupture due to abnormal communication Low platelet count : reduced ability to form blood clots Summary: Blood in poop may simply be related to a red appearance from foods, or due to a more serious gut injury

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