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doi: 10.1002/jbm.a.30662

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The compound's interaction with nitric oxide pathways supports vascular integrity in organ tissue, limiting damage from ischemic events

In the US, landmark initiatives such as the Orphan Drug Act (1983) 26 and the Accelerating Rare disease Cures program (2022) have promoted this mission by driving scientific innovation, regulatory flexibility and stakeholder engagement 27