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SAG is an orally stable glutathione that has been shown to cross the membrane of the mitochondria, which increases the organelles activity and helps minimize reactive oxygen species.*

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In a study using the psychometric HE score (PHES) in a single institution in Korea, MHE was seen in 25.6% of patients with cirrhosis, including 20.2% of those in Child-Pugh A, 42.9% in Child-Pugh B, and 60% in Child-Pugh C [310]

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