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Description
By suppressing the Nrf2 antioxidant pathway, ML385 disrupts HMOX1-mediated iron homeostasis, increasing labile iron pools that amplify venetoclax-induced mitochondrial apoptosis through ferroptotic synergy
doi: 10.1016/j.freeradbiomed.2023.12.030 179 WeiWYangLWangBTangLLiJLiuCet al
Consequently, immuno-stimulatory DAMP-release during ferroptotic cell death may further fuel ongoing inflammation and promote progression of inflammatory diseases
M.3rdet al (2021)
Audiology 10 , 13844 (1971)
