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Description
During phase I, the subjects begin forcefully exhalating against a closed airway, the intrathoracic pressure suddenly increases which leads to the brief increase in the systemic arterial blood pressure (ABP) and cerebral bloof flow

10.1111/1346-8138.12739 J

J Clin Psychiatry 2007

As an antioxidant, it helps slow down the aging process and strengthens the immune system
That negative feedback loop is part of why GH peptides can feel strong early and flat later, even before classic receptor downregulation is the whole story
