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Alveolar macrophages (AMs) secrete exosomes that transport ficolin B (Fcn B), which in turn activates the cGAS-STING pathway, accelerating autophagy and iron death in lung epithelial cells [117]
While this use is off-label, the mechanistic rationale is sound and the early data is encouraging
Verdict : Misleading
m6A-YTHDF1-mediated TRIM29 upregulation facilitates the stem cell-like phenotype of cisplatin-resistant ovarian cancer cells
