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Soga, M., Matsuzawa, A
To interrogate the potential effect of the lipidation on the Cagri-bound structures, we also determined structures of the CTR and AMY 1 R bound to a Cagri analogue lacking the N-terminal lipidation (CagriBB)
Classical benzodiazepines (diazepam, alprazolam, phenazepam) bind directly to a specific allosteric site on the GABA-A receptor, producing potent anxiolysis alongside sedation, muscle relaxation, cognitive impairment, tolerance development, and physical dependence
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