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Thirdly, patients with Down syndrome or autism have increased oxidative stress and exhibit particular disturbed profiles of one-carbon metabolism [1315]

Clinical Guidelines & Documentation

Ianello RC, Crack PJ, de Hann JB, Kola I: Oxidative stress and neural dysfunction in Down syndrome

The serum separation tubes were allowed to stand at room temperature for 15 min, centrifuged for 10 min, and serum was removed and placed into a microfuge tube