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PG are also elevated in cerebrospinal fluid of people with MS [256, 257] and COX-2 is upregulated in demyelinating MS plaques [258, 259], suggesting a potential role of those inflammatory mediators in MS

In cell and tissue models, Epithalon upregulates telomerase activity, maintains telomere length, and modulates aging-related gene expression (p16, p21) to delay senescence