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3.3 Immune checkpoints in COPD Immune responses in COPD are modulated by immune checkpoints that can either inhibit or enhance inflammation (124)

As reviewed most recently by Rice [97], ascorbate release from astrocytes and neurons has been linked in numerous studies to uptake of glutamate on one or more of its specific transporters [98-102]

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While NAD+ focuses primarily on energy production, glutathiones main role is protection

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