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they are mechanistically coupled, forming a bidirectional vicious cycle that we will dissect in the following sections

doi: 10.1038/S41574-019-0280-9 47 HompeschMJones-LeoneACarrMCMatthewsJZhiHYoungMet al

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2.5 Metabolic coupling mechanisms between neurons and astrocytes Another emerging trend is the investigation of metabolic coupling between neurons and astrocytes (Ashrafi and Ryan, 2017)