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Biochemical aspects in autism spectrum disorders: Updating the opioid-excess theory and presenting new opportunities for biomedical intervention

The serine de novo synthesis pathway (SSP) represents a pivotal metabolic bypass of glycolytic metabolism, whereby the glycolytic intermediate 3-phosphoglyceric acid is converted into serine and glycine through the action of numerous metabolic enzymes, including phosphoglycerate dehydrogenase (PHGDH)

Forming a habit of Oxoneg has not been reported

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These agents can reactivate tumor suppressor genes by demethylating promoter regions, inhibiting cancer growth, and promoting cellular differentiation - potentially attenuating the aggressive nature of cancer cells [92]