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Studies examining links between TB500 and integrin linked kinase suggest potential involvement in pathways related to cell adhesion, structural organization, and communication between cells and their surrounding matrix

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Numerous key parameters affect the efficacy of MSCs, covering aspects such as the type of transplanted cells, cell source, culture and expansion conditions, transplantation route, cell number, patient selection, and efficacy evaluation indicators

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Some individuals may live with minimal symptoms, while others require lifelong medical support