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The supernatants were transferred again into 1.5ml tubes, snap frozen in liquid N 2 and stored at 80C

For the superior sagittal sinus pressure recording, we made a single burr hole in the rostral part of the sagittal suture, above the superior sagittal sinus, and cannulated the anterior portion of the superior sagittal sinus by Braun intravenous cannulas

Hydration and electrolytes reduced food and fluid intake plus GI symptoms make dehydration a real risk

Analytical approaches for structural verification and impurity profiling, as well as global regulatory classifications and formulation-stability considerations, are also summarized