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These observations reinforce the need for well-designed randomised controlled trials (RCTs) to validate the findings and expand the evidence base

If using a skinfold, gently pinch up a fold of skin and subcutaneous tissue using your thumb and forefinger, insert the needle at a 90-degree angle, and maintain the skinfold throughout the injection until after the needle is withdrawn

This is especially true if you have a B12 deficiency

12 May 2017

Whilst there are published reports showing levels above normal can cause acne, there are no data Im aware of to show whether or not there might be a subset of patients in whom normal serum levels can trigger acne or an acne-like rash, she says