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A recent study analyzed cell type-specific gene expression changes to identify potential drug targets and genetic biomarkers associated with Alzheimers disease using single network biology 7

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Oxidative stress and docosahexaenoic acid injury-induced downregulation of ferroptosis regulator acyl-CoA synthetase long-chain family member 4 (ACSL4), increased lipid peroxidation and decreased cell viability, and lead to ferroptosis in RPE (Neiteler et al., 2023)