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Serotonergic Modulation and Mood-Related Research BPC-157s effects extend to the serotonergic system, with preclinical research demonstrating modulation of 5-HT (serotonin) neurotransmission relevant to mood, anxiety, and antidepressant biology: Forced swim test and tail suspension test: Both are standard rodent models of depressive behaviour (immobility as a despair measure)

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