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Presentation: Lyophilized powder (research use) Target: Nicotinamide Nmethyltransferase (NNMT) inhibitor Suggested Use: In vitro / preclinical workflows as defined by protocol Storage: Follow validated lab SOPs for smallmolecule lyophilizates 1

In C2C12 myotubes, NNMT inhibitor treatment produces concentration-dependent increases in NADH levels (50% higher at 30 M) and reduces NAD+/NADH ratios by 25-40%

The altered relationship with food and hunger cues can be destabilizing

For individuals with growth hormone deficiency or conditions benefiting from growth hormones broader effects, full GH may be appropriate despite side effects
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The tool has been used successfully in over 100 countries and validated in several low and middle-income countries
